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Research Article
A prospective comparison of continuous wave and micropulse transscleral laser cyclophotocoagulation for refractory glaucoma in African eyes
1 Consultant Ophthalmologist, Eye Foundation Hospital, 27 Isaac John Street, GRA Ikeja, Lagos, Nigeria
2 Senoir Registrar, Eye Foundation Hospital, 27 Isaac John Street, GRA Ikeja, Lagos, Nigeria
Address correspondence to:
Olufemi Oderinlo
Eye Foundation Hospital, 27 Isaac John Street, GRA Ikeja, Lagos 001001,
Message to Corresponding Author
Article ID: 100008O02OO2023
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Oderinlo O, Ogunro A, Hassan A, Oladeji A, Idris O. A prospective comparison of continuous wave and micropulse transscleral laser cyclophotocoagulation for refractory glaucoma in African eyes. Edorium J Ophthalmol 2023;6(1):1–6.ABSTRACT
Aims: To report the efficacy of transscleral diode laser photocoagulation and compare outcomes between the continuous wave (CW) and micropulse wave (MP) protocols for refractory glaucoma in African eyes.
Methods: A non-randomized prospective comparative study of patients who had transscleral diode laser photocoagulation for refractory glaucoma between January 2021 and December 2021in Eye Foundation Hospital Lagos, Nigeria was done.
Results: A total of 52 eyes of 52 patients were analyzed. Mean age of patients was 66 ± 12.5 years. The mean preoperative intraocular pressure (IOP) was 31.2 ± 11.9 mmHg. Overall post-operative mean IOP was 17.9 ± 8.6 mmHg at 4 weeks, 21.0 ± 9.9 mmHg at 8 weeks and 20.6 ± 11.4 mmHg at 12 weeks. The difference between mean preoperative and postoperative IOP measured at week 12 was statistically significant (p<0.001). Both continuous wave and micropulse wave protocols were effective at reducing intraocular pressures, the micropulse group had a mean difference between preoperative IOP and postoperative IOP at week 12 of 7.5 ± 6.7 mmHg (p=0.001), while the continuous wave laser group had a mean difference of 11.7 ± 13.7 mmHg (p<0.001). The micropulse group achieved a higher percentage of success in 11 eyes (78.6%) compared with 24 eyes (63.2%) in the continuous wave group. This difference was not statistically significant (p=0.341).
Conclusion: Both the continuous wave (CW) and micropulse wave (MP) protocols of transscleral diode laser photocoagulation were found effective at significantly reducing IOP in our study of African eyes with refractory glaucoma. Although the MP group achieved a higher percentage of absolute success, this was not statistically significant.
Keywords: Continuous wave transscleral laser photocoagulation, Micropulse transscleral laser photocoagulation, Refractory glaucoma, Transscleral laser cyclophotocoagulation
SUPPORTING INFORMATION
Acknowledgments
We appreciate Mr. Dipo Odunusil (records staff) for his invaluable contribution to record keeping for our study.
Author ContributionsOlufemi Oderinlo - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Adunola Ogunro - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Adekunle Hassan - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Abiola Oladeji - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Oyekunle Idris - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Olufemi Oderinlo et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
