Case Report


Utilization of nano-hydroxyapatite mixed with platelet rich fibrin for reconstruction of severe atrophied over pneumatized maxilla: A case report

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1 Implantology Department, Associação Brasileira de Odontologia, Mato Grosso, Brazil

2 Implantology Department, State University of Rio de Janeiro, Rio de Janeiro, Brazil

3 Ortodontic Department, University of Barcelona, Barcelona, Spain

4 Implantology Department, Portuguese Catholic University, Lisbon, Portugal

5 Laboratory of Ultrastructure and Tissue Biology, Department of Histology and Embryology, State University of Rio de Janeiro, Rio de Janeiro, Brazil

Address correspondence to:

Igor da Silva Brum

Implantology Department, State University of Rio de Janeiro, Rio de Janeiro,

Brazil

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Article ID: 100042D01GV2021

doi: 10.5348/100042D01GV2021CR

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How to cite this article

Vinholi GH, Brum IS, Devita RL, Amorim JCL, de Carvalho MAA, de Carvalho JJ. Utilization of nano-hydroxyapatite mixed with platelet rich fibrin for reconstruction of severe atrophied over pneumatized maxilla: A case report. Edorium J Dent 2021;8:100042D01GV2021.

ABSTRACT


Introduction: With the current need for large bone reconstructions due to very robust losses in skeletal architecture, not only of the maxillary and mandibular regions but also in other regions of the body, this guided bone regeneration has been increasingly used.

Case Report: A leukoderma patient at 52 years of age sought the implantology clinic of the Brazilian Dental Association (ABO) to solve his case of tooth loss. The patient presented overly aggressive bone loss in the total maxilla, and, because of this, it was planned to reconstruct the lost area with a synthetic particulate nano-biomaterial (Blue Bone, Curitiba, Brazil), with the help of the platelet aggregate (PRF). For the surgery, 6 grams of this biomaterial were used, in the anterior region of the maxilla, tent screws were placed to stabilize the grafted bilateral and maxillary sinus lifting surgeries were performed in the posterior regions. The entire regenerated area was covered with L-PRF membrane for better stability and healing. An incredibly significant gain in bone volume was observed six months after surgery throughout the regenerated region, enabling the placement of dental implants (Systhex, Curitiba, Brazil) and later the placement of the supported prosthesis.

Conclusion: The nano graft presented a very favorable result in the gain of bone volume, proving to be an excellent indication for more severe cases of bone loss.

Keywords: Biomaterial, Graft, Nano-hydroxyapatite, PRF

SUPPORTING INFORMATION


Acknowledgments

This research received financial support from the Brazilian Research Agency CNPq, FAPERJ, UERJ, Capes, and Lubt.

Author Contributions

Gustavo Helder Vinholi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Igor da Silva Brum - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Renan Lana Devita - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

João Carlos Lopes Amorim - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Marco Antônio Alencar de Carvalho - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Jorge José de Carvalho - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2021 Gustavo Helder Vinholi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.