Case Report


Atypical case of pulmonary Langerhans cell histiocytosis presenting as miliary nodules

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1 Internal Medicine, MercyONE North Iowa, Mason City, IA, USA

2 Pulmonology, MercyONE North Iowa, Mason City, IA, USA

Address correspondence to:

Michelle Low

652 S Tennessee Pl, Mason City, IA 50401,

USA

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Article ID: 100106Z06ML2022

doi: 10.5348/100106Z06ML2022CR

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How to cite this article

Low M, Lasley K, Singh P. Atypical case of pulmonary Langerhans cell histiocytosis presenting as miliary nodules. Case Rep Int 2022;11:100106Z06ML2022.

ABSTRACT


Pulmonary Langerhans cell histiocytosis (PLCH) is a rare smoking-related interstitial lung disease affecting primarily young adult smokers. Diagnosis is made with typical radiographic findings of centrilobular nodules and cystic lesions on high resolution computed tomography (HRCT) confirmed with tissue biopsy. We describe a case of a 59-year-old man presenting with chronic tobacco use and cough who was found to have an atypical radiographic finding of miliary nodules on HRCT that was confirmed as PLCH on transbronchial lung biopsy.

Keywords: Interstitial lung disease, Miliary nodules, Pulmonary Langerhans cell histiocytosis, Smoking

SUPPORTING INFORMATION


Author Contributions

Michelle Low - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Katharine Lasley - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published

Pranav Singh - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2022 Michelle Low et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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