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Case Report
Moebius syndrome: A case report from Indonesia
1 Neurologist, Bhayangkara Raden Said Sukanto Hospital, Jakarta, Indonesia
2 Medical Doctor, Faculty of Health and Medicine, Atma Jaya Catholic University, Jakarta, Indonesia
Address correspondence to:
Maula N Gaharu
Email: mgaharu@yahoo.com,
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Article ID: 100107Z06MG2022
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How to cite this article
Gaharu MN, Frederickson S, Natalia M. Moebius syndrome: A case report from Indonesia. Case Rep Int 2022;11:100107Z06MG2022.ABSTRACT
Introduction: Moebius syndrome is a neurological condition characterized by congenital facial uniplegia or diplegia due to peripheral type facial nerve paresis and lateral eye movement paresis due to abducens nerve paresis resulting in strabismus. Incidence of Moebius syndrome is 0.27/100,000 live births and often associated with abortion attempts. The following is a case report of Moebius syndrome in Indonesia of a 14-year-old girl with a history of attempted abortion by her mother.
Case Report: A 14-year-old girl came with facial muscle complaints in the form of difficulty in raising both eyebrows and closing the mouth since birth. These complaints cause difficulty in eating and drinking. Complaints accompanied by abnormality of the limbs and the number of finger in toes and hands. The patient’s mother had a history of attempted abortion by taking the chemical disinfectant chloroxylenol 4.8% and other drugs. There was bilateral facial nerve paresis and cognitive impairment. On examination of brain magnetic resonance imaging (MRI), it was within normal limits. The patient was planned for physiotherapy and consulted to orthopedics.
Conclusion: Moebius syndrome is a collection of rare neurological clinical manifestations in children. Exposure to chemicals during pregnancy can be the etiology of this syndrome in addition to genetics. Management of Moebius syndrome is limited to supportive and symptomatic approach.
Keywords: Chloroxylenol, Cognitive impairment, Facial nerve, Moebius syndrome
SUPPORTING INFORMATION
Acknowledgments
We are grateful to our patient.
Author ContributionsMaula N Gaharu - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sandy Frederickson - Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Maria Natalia - Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Maula N Gaharu et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
