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Case Report
Laminar heterotopia: A rare cause of epilepsy and mental retardation
1 Resident Physician, Radiology Department, UHC Ibn Sina, Rabat, Morocco
2 Professor at the Radiology, Mohamed V Military Instruction Hospital, Rabat, Morocco
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Merbouh Sahar
CHU Ibn Sina, Rabat,
Morocco
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Article ID: 100114Z06MS2023
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How to cite this article
Sahar M, Dokal DI, Hassan N. Laminar heterotopia: A rare cause of epilepsy and mental retardation. Case Rep Int 2023;12(1):9–11.ABSTRACT
Neuronal migration disorders are a category of developmental brain disorders leading to cortical dysplasia. Laminar heterotopia is a form of diffuse gray matter heterotopia, which can result from a failure of proliferation, migration, or organization of neuronal and glial cells in the developing cortex leading to cortical dysplasia. The etiopathogenesis of this malformation remains a subject of discussion. Band heterotopia or double cortex are frequently shown if not always of genetic origin (mutation of genes coding for neuronal migration). We report the case of a young patient who presented episodes of complex seizures since childhood and mild mental retardation.
Keywords: Double cortex, Laminar heterotopia, Magnetic resonance imaging
SUPPORTING INFORMATION
Author Contributions
Merbouh Sahar - Revising it critically for important intellectual content, Final approval of the version to be published
Diallo Ibrahima Dokal - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nouali Hassan - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Merbouh Sahar et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
