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Case Report
Late occurrence of ChAdOx1 vaccine-induced myocarditis presenting with ventricular arrhythmia
1 MBBS, MD, DM, Director Cardiology, Supreme Hospital, Delhi NCR, India
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Deepak Natarajan
MBBS, MD, DM, Director Cardiology, Supreme Hospital, Delhi NCR,
India
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Article ID: 100116Z06DN2023
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Natarajan D, Rana P. Late occurrence of ChAdOx1 vaccine-induced myocarditis presenting with ventricular arrhythmia. Case Rep Int 2023;12(1):18–22.ABSTRACT
A 51-year-old woman who had received 2 injections of a ChAdOx1 vaccine in 2021 and a booster dose in 2022 was recently admitted for central chest pain accompanied with palpitations for the previous 2 weeks. She was negative for the COVID-19 virus, troponin was not elevated, both the 12-lead electrocardiogram and 2D echocardiogram were normal. At peak exercise during exercise treadmill test she developed a single ventricular couplet, but coronary angiography revealed normal coronary arteries. A 24-hour electrocardiogram recording revealed symptomatic non-sustained ventricular tachycardia while she was in bed. A 3T cardiac magnetic resonance imaging (MRI) demonstrated late gadolinium sub-epicardial uptake at the left ventricle apex suggesting fibrosis. The patient was diagnosed as late presentation of myocarditis following ChAdOx1 vaccination, and was discharged on oral amiodarone and colchicine.
Keywords: Adenoviral vector vaccine, Cardiac MRI, COVID vaccine myocarditis, Myocarditis, Non-sustained ventricular tachycardia, SARS-CoV-2
SUPPORTING INFORMATION
Author Contributions
Deepak Natarajan - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Poonam Rana - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Deepak Natarajan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
